Donald Gullberg from the Department of Biomedicine, University of Bergen, will give a talk entitled “α11β1, a mesenchymal collagen-binding integrin with a central role in tissue- and tumor fibrosis”.
Position: Professor, group leader of the Matrix Biology research group and PI at the Center for Cancer Biomarkers (CCBIO) Research field: The study of integrin α11 in the context of tissue and tumor fibrosis. Major projects within the group aim to further understand the role of the collagen receptor α11β1 and other fibroblast integrins during health and in disease. Seminar focus: Collagen-binding integrins are predicted to play an important role in matrix remodeling in fibrotic diseases. Data suggesting a role of integrin α11β1 in matrix assembly will be presented. Thursday, May 19, 14.30
Manfred Jung from the Albert-Ludwigs-Universität Freiburg, Germany, will give a talk entitled “Chemical epigenetics – targeting reversible histone acetylation”.
Position: Professor for Pharmaceutical Chemistry Research field: Chemical Epigenetics Main achievements: Prof. Dr. Manfred Jung is leading the Chemical Epigenetics Group at Institute of Pharmaceutical Science, Albert-Ludwigs-Universität Freiburg, Germany. He has received multiple awards, including the Phoenix Prize for Pharmaceutical Chemistry in 2016 and the Eugen Graetz Award of the University of Freiburg 2004. Seminar focus: The seminar will focus on new chemical and biochemical tools to dissect biological pathways, validate therapeutic targets, and discover and optimize potential drugs addressing a wide range of epigenetic targets. This includes new biochemical and biophysical assays for histone deacetylases (HDACs) and sirtuins, and newly identified targets converted into functionalized tools for chemical biology.
