Conformational analysis of membrane-proximal segments of GDAP1 in a lipidic environment using synchrotron radiation suggests a mode of assembly at the mitochondrial outer membrane.
Sutinen A, Jones NC, Hoffmann SV, Ruskamo S, Kursula P. Biophys Chem. 2023 Sep 25;303:107113. doi: 10.1016/j.bpc.2023.107113. Online ahead of print.PMID: 37778197
Three-dimensional nanofibrous sponges with aligned architecture and controlled hierarchy regulate neural stem cell fate for spinal cord regeneration.
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Inhibition of extracellular vesicle-derived miR-146a-5p decreases progression of melanoma brain metastasis via Notch pathway dysregulation in astrocytes.
Rigg E, Wang J, Xue Z, Lunavat TR, Liu G, Hoang T, Parajuli H, Han M, Bjerkvig R, Nazarov PV, Nicot N, Kreis S, Margue C, Nomigni MT, Utikal J, Miletic H, Sundstrøm T, Ystaas LAR, Li X, Thorsen F. J Extracell Vesicles. 2023 Oct;12(10):e12363. doi: 10.1002/jev2.12363.PMID: 37759347 Free PMC article.
Extending protein interaction networks using proteoforms and small molecules.
Hernández Sánchez LF, Burger B, Castro Campos RA, Johansson S, Njølstad PR, Barsnes H, Vaudel M. Bioinformatics. 2023 Sep 26:btad598. doi: 10.1093/bioinformatics/btad598. Online ahead of print.PMID: 37756698
Cognitive function in patients with irritable bowel syndrome: impairment is common and only weakly correlated with depression/anxiety and severity of gastrointestinal symptoms.
Billing J, Berentsen B, Lundervold A, Hillestad EMR, Lied GA, Hausken T, Lundervold AJ. Scand J Gastroenterol. 2023 Sep 20:1-9. doi: 10.1080/00365521.2023.2256916. Online ahead of print.PMID: 37727887
Use of big data and machine learning algorithms to extract possible treatment targets in neurodevelopmental disorders.
Malik MA, Faraone SV, Michoel T, Haavik J. Pharmacol Ther. 2023 Oct;250:108530. doi: 10.1016/j.pharmthera.2023.108530. Epub 2023 Sep 12.PMID: 37708996 Free article. Review.
PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities.
Đukić N, Strømland Ø, Elsborg JD, Munnur D, Zhu K, Schuller M, Chatrin C, Kar P, Duma L, Suyari O, Rack JGM, Baretić D, Crudgington DRK, Groslambert J, Fowler G, Wijngaarden S, Prokhorova E, Rehwinkel J, Schüler H, Filippov DV, Sanyal S, Ahel D, Nielsen ML, Smith R, Ahel I. Sci Adv. 2023 Sep 15;9(37):eadi2687. doi: 10.1126/sciadv.adi2687. Epub 2023 Sep 13.PMID: 37703374 Free PMC article.
Forward genetics and functional analysis highlight Itga11 as a modulator of murine psoriasiform dermatitis.
Bieber K, Bezdek S, Gupta Y, Vorobyev A, Sezin T, Gross N, Prüssmann J, Sayegh JP, Becker M, Mousavi S, Hdnah A, Künzel S, Ibrahim SM, Ludwig RJ, Gullberg D, Sadik CD. J Pathol. 2023 Oct;261(2):184-197. doi: 10.1002/path.6162. Epub 2023 Aug 11.PMID: 37565309
Ablation of integrin-mediated cell-collagen communication alleviates fibrosis.
Sawant M, Wang F, Koester J, Niehoff A, Nava MM, Lundgren-Akerlund E, Gullberg D, Leitinger B, Wickström S, Eckes B, Krieg T. Ann Rheum Dis. 2023 Jul 21:ard-2023-224129. doi: 10.1136/ard-2023-224129. Online ahead of print.PMID: 37479494