Hani Goodarzi from the University of California San Francisco, USA, will give a talk entitled “Revealing the regulatory code underlying pathological regulation of RNA dynamics in metastasis”.
Position: Associate Professor, Department of Biochemistry & Biophysics, Bakar Computational Health Sciences Institute, Helen Diller Family Comprehensive Cancer Center.
Research field: Translational control of metastatic spread.
Main achievements: Most recently: 2021: Vilcek Prize for Creative Promise in Biomedical Sciences & 2021: Mark Foundation ASPIRE Award.
Seminar focus: Widespread aberrant splicing is now considered a hallmark of cancer, and many of the resulting transcript isoforms have been functionally implicated in tumorigenesis. However, the underlying regulatory pathways that govern RNA splicing and the extent to which they play a role in cancer progression remain largely unknown. Here, Dr. Goodarzi will present his ongoing efforts to uncover the underlying regulatory information that is encoded in the RNA sequence, its structure, and its binding partners.
Chairperson: Nils Halberg <nils.halberg@uib.no>
Thursday, June 9, 14.30
CCBIO Seminar
Torsten O. Nielsen from the Faculty of Medicine, University of British Columbia, Canada, will give a talk entitled “Breast cancer biomarker development: intrinsic subtypes, Ki67 and proteomics”.
Position: Professor in Pathology and Laboratory Medicine.
Research field: Professor Nielsen is a clinician-scientist pathologist who has chosen to dedicate his career to translating basic science of cancer into new diagnostics and new therapies. His research has to date has focused on breast cancer and sarcomas. He provides pathology input into translational cancer research, bringing his skills in genomics and biomarker development into clinical trial design and the development of diagnostics that truly improve patient care.
Main achievements: Major accomplishments include development of the PAM50 algorithm and FDA-cleared Prosigna assay; leading international standardization of Ki67 testing; and key work uncovering the biology of three kinds of sarcoma each of which led to new diagnostics and clinical trials of new therapies.
Seminar focus: Breast cancer proteomics and perspectives on patient stratification.
Chairperson: Lars A. Akslen <Lars.Akslen@uib.no>
Monday, June 13, NB! 13.00 at the auditorium in Armauer Hansens Hus
