Targeting the molecular chaperone CCT2 inhibits GBM progression by influencing KRAS stability.
Zhao F, Yao Z, Li Y, Zhao W, Sun Y, Yang X, Zhao Z, Huang B, Wang J, Li X, Chen A.Cancer Lett. 2024 Apr 4:216844. doi: 10.1016/j.canlet.2024.216844. Online ahead of print.PMID: 38582394
What makes mentors thrive? An exploratory study of their satisfaction in undergraduate medical education.
Skjevik EP, Schei E, Boudreau JD, Tjølsen A, Ringberg U, Fuks A, Kvernenes M, Ofstad EH.BMC Med Educ. 2024 Apr 4;24(1):372. doi: 10.1186/s12909-024-05344-y.PMID: 38575953 Free PMC article.
Generation of an enhancer-driven gene expression viral tool specific to dentate granule cell-types through direct hippocampal injection.
Potenza ML, Blankvoort S, Carvalho MM, Grimstvedt JS, Di Maria V, Moan K, Nair RR, Flatset MS, Zhang Q, Thomas LF, Pauzin FP, Da Silva Mazzarini Baldinotti R, Quattrocolo G, Bramham CR, Sætrom P, Witter MP, Kentros CG.Front Neurosci. 2024 Mar 14;18:1274174. doi: 10.3389/fnins.2024.1274174. eCollection 2024.PMID: 38550563 Free PMC article.
Natalizumab promotes anti-inflammatory and repair effects in multiple sclerosis.
Lereim RR, Nytrova P, Guldbrandsen A, Havrdova EK, Myhr KM, Barsnes H, Berven FS. PLoS One. 2024 Mar 25;19(3):e0300914. doi: 10.1371/journal.pone.0300914. eCollection 2024.PMID: 38527011 Free PMC article.
Protein N-terminal acetylation is entering the degradation end game.
Arnesen T, Kjosås I, McTiernan N. Nat Rev Mol Cell Biol. 2024 Mar 22. doi: 10.1038/s41580-024-00723-1. Online ahead of print.PMID: 38519774 No abstract available.
Blind deconvolution decreases requirements on temporal resolution of DCE-MRI: Application to 2nd generation pharmacokinetic modeling.
Kratochvíla J, Jiřík R, Bartoš M, Standara M, Starčuk Z Jr, Taxt T. Magn Reson Imaging. 2024 Jun;109:238-248. doi: 10.1016/j.mri.2024.03.019. Epub 2024 Mar 19.PMID: 38508292
Local patterns of genetic sharing challenge the boundaries between neuropsychiatric and insulin resistance-related conditions.
Fanelli G, Franke B, Fabbri C, Werme J, Erdogan I, De Witte W, Poelmans G, Ruisch IH, Reus LM, van Gils V, Jansen WJ, Vos SJB, Alam KA, Martinez A, Haavik J, Wimberley T, Dalsgaard S, Fóthi Á, Barta C, Fernandez-Aranda F, Jimenez-Murcia S, Berkel S, Matura S, Salas-Salvadó J, Arenella M, Serretti A, Mota NR, Bralten J. medRxiv [Preprint]. 2024 Mar 8:2024.03.07.24303921. doi: 10.1101/2024.03.07.24303921.PMID: 38496672 Free PMC article. Preprint.
Genome-wide association study identifies new loci associated with OCD.
Strom NI, Halvorsen MW, Tian C, Rück C, Kvale G, Hansen B, Bybjerg-Grauholm J, Grove J, Boberg J, Nissen JB, Damm Als T, Werge T, de Schipper E, Fundin B, Hultman C, Höffler KD, Pedersen N, Sandin S, Bulik C, Landén M, Karlsson E, Hagen K, Lindblad-Toh K; Nordic OCD and Related Disorders Consortium (NORDiC); 23andMe Research Team; PGC TS/OCD working group; Hougaard DM, Meier SM, Hellard SL, Mors O, Børglum AD, Haavik J, Hinds DA, Mataix-Cols D, Crowley JJ, Mattheisen M.medRxiv [Preprint]. 2024 Mar 8:2024.03.06.24303776. doi: 10.1101/2024.03.06.24303776.PMID: 38496634 Free PMC article. Preprint.